ABSTRACT
Background and aim: The corona epidemic and its impact on the society led the government policy to support the production of medicine and related vaccines. Vaccination is known to be an effective preventive measure and eradication of this disease. However, information on different brands of vaccines at different times, age groups, occupations or underlying diseases is not available. The present study intends to compare incidence of COVID-19 after AstraZeneca, Sinopharm and Sputnik vaccination in patients referred to hospitals affiliated to Shoushtar University of Medical Sciences, 2021. Also determine the effect of vaccination in reducing the severity of symptoms and death and the necessary information and education to the public about the possibility of coronavirus after vaccination, to continue to follow health protocols. Method(s): The present study is a retrospective cross-sectional study In order to evaluate and compare the rate of covid-19 and the death rate in vaccinated people in Shoushtar,Iran. The study population of this study includes people who have received one or two doses of Corona vaccine Sputnik V, Sinopharm and AstraZeneca and have referred to medical centers affiliated to Shoushtar University of Medical Sciences (May 2021 to september 2021). 639 Samples were selected based on inclusion criteria from the research community. Patient information including demographic information, information on vaccines, underlying diseases, severity of COVID-19 symptoms, length of hospital stay and previous history of COVID-19. Statistical analysis was performed using Chi-square, Anova at a significance level of 0.05, with SPSS.V18 software. Result(s): The mean age of study participants was 56.58 years. The median duration of infection after vaccination was 30(IQR: 20-50) days, with the range (4-180).46.9% of patients were admitted to routine hospital wards and 4.1% of patients were admitted to intensive care units. The prevalence of covid-19 infection in vaccinated is 0.3% in total. There is a significant difference between the three types of vaccines in terms of the proportion (p<0.001). The prevalence of covid-19 in patients vaccinated with Sputnik vaccine was (2.6%) and in Sinopharm vaccine (0.25%). the mortality rate in Sputnik vaccine was zero and in Astrazeneca vaccine was more than Sinopharm vaccine (p = .029) Conclusion(s): The results of the present study showed that the rate of death and re-infection in the used vaccines is different, so that re-infection in Sputnik vaccine was more than other vaccines (2.7%), but the duration of hospitalization in this vaccine was less than the others. Also, the death rate in Astrazanka vaccine was higher than others. The mean incidence of COVID-19 was 42.31 days after vaccination;the lowest incidence was reported 4 days after vaccination. Only 5% of patients needed to be admitted to the intensive care unit;the maximum length of hospital stay was estimated to be 3 to 4 days. Copyright © 2022, Anka Publishers. All rights reserved.